For daily driving, you shouldn't have any issues. I lived in Boulder, CO for several years with my TJ and noticed no difference in performance between any driving around there and when I lived in TX or MN. As for off-roading, I can't say as I didn't get into any off road stuff back then, but I imagine that it will depend more on the ruggedness of the terrain you aim to tackle and size of tires you run more than any effect of the elevation.