Not that it is a deal breaker, but how buzzy/loud/annoying is the engine cruising in the 2750ish RPM range if at all? Does the 4.0l care?
FYI...the stroker is going to be a DIY combo of the "modified poor man's stroker" and either a gasket-matched head done by myself or if I want to cough up some coin get the ported TUPY head from Newcomer. Probably a Comp Cam's 231 or 232 cam. Shooting for 9.5:1 compression or so and 87-89 octane. Prioritizing low and mid range torque.
My stroker is not buzzy at any rpm really. The inherent smoothness of the straight six remains. The block I have is 1992 (IIRC) and pre-dates some changes Chrysler to later 90s block (which were stamped NVH). I presume because of that and heavier valve springs, there is a little more mechanical noise from the motor vs the stock 4.0 (which I don't notice anymore). Chad Golen said "Cam specs are Duration @ .050” 210/219 Lift .500”/.500” LSA 114".
Back to RPM/gearing: at 75 MPH I'm at 2500 which is fine. I have a full 2.5" exhaust w/ a smaller cat and Magnaflow muffler which sound good to me but are loud enough as you approach 3K that I wouldn't like it for cruising. One more thing, as you start doing things which can lead to driveline vibes (lifts/tucks...), higher RPM can make that worse. So, in my view, one advantage the increased power from a stroker is slightly less need for deeper gears especially for street driving.
bottom line: 4.56 is the lowest I recommend.