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Why we might not get a coronavirus vaccine


Reign Mack

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"Vaccines are simple in principle but complex in practice. The ideal vaccine protects against infection, prevents its spread, and does so safely. But none of this is easily achieved, as vaccine timelines show.

More than 30 years after scientists isolated HIV, the virus that causes Aids, we have no vaccine. The dengue fever virus was identified in 1943, but the first vaccine was approved only last year, and even then amid concerns it made the infection worse in some people. The fastest vaccine ever developed was for mumps. It took four years."

"During the search for a Sars vaccine in 2004, scientists found that one candidate caused hepatitis in ferrets. Another serious concern is “antibody-induced enhancement” where the antibodies produced by a vaccine actually make future infections worse. The effect caused serious lung damage in animals given experimental vaccines for both Sars and Mers. "

So far, the Sars-CoV-2 coronavirus seems fairly stable, but it is acquiring mutations, as all viruses do. Some genetic changes have been spotted in the virus’s protein “spikes” which are the basis of most vaccines. If the spike protein mutates too much, the antibodies produced by a vaccine will effectively be out of date and might not bind the virus effectively enough to prevent infection. "

 
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jeepins

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I've never felt that will ever find a cure for this. Have to just let it run its course like those others did.
 
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WallyWest

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Nov 6, 2019
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Yeah, I've been hearing from the start from people who know vaccines well that Corona won't be easy to make a vaccine for. Maybe impossible.

We will "cure" it by simply ignoring it. The latest paper from the CDC shows it's actual death rate lower than the flu. And every week the numbers keep getting revised down.