Well places like Flyin Ryan Performance or HemiFever offer canned tunes plus you can get different tunes for using different octane.
It isn't always about squeezing that last 2-3 HP at wide open throttle. It's more about that range you drive in that you can get some improvements.
From some of the articles I've read the cams used in Jeep & Dodge engines are always on the lower end of performance. So replacing it is a good idea. Adding a tune on top of that is just icing on your cake. Heck no it ain't gunna outperform a Eco Boost truck or some tuner Honda but that isn't the point.
Since you are going to regear why are you only going to 4.88 gears and not 5.13 gears?