This makes a massive difference, regardless of the type of heating/cooling system used.
This can't be stated enough ! Super insulation is the concept we used when we built our home in the mid 80's.
The wall sections are R - 45 and the ceiling is R - 41. A heat loss study was performed on the house and it takes 216 btus per degree difference from the inside temp to the outside temp. In other words if it's - 30 F. outside and 70 F. inside it requires 21,600 btu's per hour for our small 1344 sq. ft. home at 9052' elevation in the Rockies . We heat with a biomass stove and " waste heat " from appliances and cooking.