Only if you are running a minimum of bump stop extension, which usually comes along relocated upper shock mounts. And if the 35X12.5 is actually a 35X12.5 like an MTR. In that case, a highline fender will get you an additional ~3/8" of flex.
This is my 35x12.5 Patagonia with a 10.75" shock divided roughly in half, relocated upper mounts and MCE flares. The tire is closer to 34".
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To get full stuff and full lock...
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...this section needs to go away.
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35s on stock shock mounts will have far fewer conflicts with stock fenders and flares.
I was looking at the Poison Spyder negative flares so definitely no issue with the red and probably no issue with the green either.
Then again, from the looks of it maybe I can save myself the money all together.
What suspension lift do you have? Body lift?