Practically speaking, you might catch someone having a one way conversation unless both parties using the repeater are in simplex range which isn't typical expect in specific use cases (like what I mentioned above).
You won't hear the nerds on GMRS simplex because their radios are transmitting on 467.XXX. The only thing you'll hear is the repeated transmission from the repeater (so, you'll hear all nerds pinging the repeater), which is on 462.XXX, same as the simplex channels.
I figured all of this stuff out because I keep my GMRS radio on in my daily driver while commuting 30 miles to work and back. For months, there was almost no activity. Then one day, I started hearing activity on GMRS 20 during every commute, and sometimes it was none-stop, depending on how chatty the nerds were. I started paying attention to call signs and then looking them up. They were from nerds all over the USA. I thought, "How can that be?" One day, I heard a computer-generated voice announce a call sign, and that put all the pieces together for me. Through some Google-sleuthing, I discovered that a new open repeater (broadcasting a call sign automatically every 20 minute or so) had been installed in a nearby city, and it is a "Node" on "The Roadkill Nationwide" Internet-connected GMRS Live Network. It turns out that I'm not a fan of connecting repeaters via the Internet. It creates way too much traffic on a channel because anyone connected to a repeater that is a "Node" goes out to all other Nodes across the USA! It's like repeater nerds on steroids. I'll bet you can do the same thing with an App on a phone, and keep the GMRS airwaves less cluttered...