Great topic. I am still trying to make my garage work as a working area as well as park a vehicle in it (27'x10). I have always stressed personal protection equipment. Safety glasses(!), appropriate gloves, steel toed boots, long sleeve and pants. Also good house keeping--Keep everything organized and alleviate any tripping hazards (power cords, blocks of wood, etc..). Sometimes when I am working on a project I stop for about 5 min and pick up my work area because it does tend to accumulate various tools, and bits and pieces of whatever I am working on.
I plan to paint mine this summer. I have one single LED bulb in there that I am hoping to convert to an 8' LED strip as well as paint the walls white. Right now they are just bare sheetrock and tape.
I threw this up to keep the rif raf away:
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