No, it is never happy, and I have adjusted it in 1* increments followed by a test drive, from 3* higher than pinion to 5* lower than pinion* with no change in severity. I've also changed control arms from Currie to OEM, to MC.
In my case, the vibes are speed related. I can jamb thru the gears hard from 1st thru 4th and it is smooth as butter. Get up to 55mph crusing speed, up hill, down hill, straight level, coasting out of gear, it doesn't matter. The vibes start to kick in at 55mph and get a bit worse at 65mph on up. I've also tested it with the rear axle on jack stands so that just the rear is spinning and can duplicate the vibes. I've been thru 3 rear drive shafts in 2 years trying to find the rainbow unicorn of balanced drive shafts with no luck.